LIV-1 / SLC39A6 Recombinant Protein

• Background:

  LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

• NCBI Gene ID:

  25800

• Swiss Prot:

  Q13433

• Accession Number:

  XP_011524203.1

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  60.1 kDa

• Applications Notes:

  This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.1 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

• NCBI Official Name:

  Solutecarrierfamily39member6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  D L Manning, et al. Mol Cell Endocrinol. 1988. 59 (3) :205-12.

• Background Reference 02:

  Kathryn M Taylor, et al. Biochem J. 2003. 375 (Pt 1) :51-9.

• Other Product Names:

  SLC39A6, LIV-1, ZIP6, Zinc transporter ZIP6, ZIP-6

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3