Products for Research Use Only
RegisterLogin

IL2 Recombinant Protein (e.coli Expressed)

CAT: 0223-97-076Size: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-97-076Size:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Interleukin-2 (IL-2) is an interleukin, a type of cytokine immune system signaling molecule, which is a leukocytotrophic hormone that is instrumental in the body's natural response to microbial infection and in discriminating between foreign (non-self) and self. IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes, the cells that are responsible for immunity. Mature human IL-2 shares 56% and 66% aa sequence identity with mouse and rat IL-2, respectively. Human and mouse IL-2 exhibit crossspecies activity. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is also necessary during T cell development in the thymus for the maturation of a unique subset of T cells that are termed regulatory T cells (T-regs) . After exiting from the thymus, T-Regs function to prevent other T cells from recognizing and reacting against "self antigens", which could result in "autoimmunity". T-Regs do so by preventing the responding cells from producing IL-2. Thus, IL-2 is required to discriminate between self and non-self, another one of the unique characteristics of the immune system.
CAS Number
9000-83-3
NCBI Gene ID
3558
Swiss Prot
P60568
Accession Number
P60568
Tag
Tag free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Chemokines & Cytokines, Immunology, Infectious Disease, Neuroscience, Signal Transduction, Stem Cell
Purity
>95% as determined by SDS-PAGE.
Buffer
Lyophilized from 0.22 um filtered solution in PBS, pH5.0. Normally trehalose is added as protectant before lyophilization
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
15.4 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Interleukin 2
NCBI Organism
Homo sapiens
Background Reference 01
Gaffen, S.L. and K.D. Liu, 2004, Cytokine 28:109.
Background Reference 02
Kasakura S, Lowenstein L, 1965, Nature 208 (5012) : 794–795.
Background Reference 03
Smith KA, Favata MF, Oroszlan S, 1983, J. Immunol. 131 (4) : 1808.
Background Reference 04
Thornton AM, Shevach EM, 1998, J. Exp. Med. 188 (2) : 287–96.
Other Product Names
IL2, TCGF, lymphokine, Interleukin 2
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized

Related Products

CatalogName
35-161E. coli Antibody
35-165E. coli Antibody
96-519LIF Recombinant Protein (HEK293 Expressed)
35-455E coli Antibody [1011]
35-164E. coli Antibody (biotin)
35-163E. coli Antibody (HRP)
35-167E. coli Antibody (HRP)
35-168E. coli Antibody (biotin)
35-166E. coli Antibody (FITC)
35-459E coli Antibody [1061]

Alternative Products

CatalogName
E53A02334GroEL, E.coli, Recombinant, expressed in E.coli
E53A02335GroES, E.coli, Recombinant, expressed in E.coli
GTR18906740IL2 Recombinant Protein (e.coli Expressed)
20419ES10Aprotinin, Recombinant, Expressed in E.coli
E53A01881Disulfide oxidoreductase (DsbA) E.coli, Recombinant, expressed in E.coli
OM770105-01Recombinant Human CNTF (E.coli-expressed)
RK20565-01PNGase F, Recombinant (Expressed in E.coli)
BL10718_R-01Recombinant Mouse Thrombopoietin (E. Coli Expressed)
OM770110-01Recombinant Human FGF8b (E.Coli-expressed)
OM770101-01Recombinant Human GDNF (E.coli-expressed)

Popular Products