IL-1RAcP Recombinant Protein

• Background:

  Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1 alpha, IL1 beta and IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.

• NCBI Gene ID:

  3556

• Swiss Prot:

  Q9NPH3

• Accession Number:

  Q9NPH3

• Tag:

  C-Fc-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Chemokines & Cytokines

• Buffer:

  Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4 . It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  39.7 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Interleukin 1 receptor accessory protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Interleukin-1 Receptor Accessory Protein, IL-1 Receptor Accessory Protein, IL-1RAcP, Interleukin-1 Receptor 3, IL-1R-3, IL-1R3, IL1RAP, C3orf13, IL1R3, IL-1 R3

• Species:

  Human

• Protein ID:

  78070603

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3