IL-6 non-lytic Recombinant Protein

• Background:

  Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130) . IL-6 is a key factor for the growth of plasma cells.

• NCBI Gene ID:

  3569

• Swiss Prot:

  Q01638

• Accession Number:

  NP_000591

• Tag:

  Fc Tag

• Type:

  Recombinant Proteins

• Source:

  CHO cells

• Field of Research:

  Cancer, Chemokines & Cytokines, Immunology, Neuroscience, Obesity, Signal Transduction

• Buffer:

  Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μ l sterile water. Add 1X PBS to the desired protein concentration.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.

• Applications Notes:

  This recombinant proteins is for research use only.

• NCBI Official Name:

  Interleukin 6

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Interleukin-6, B Cell Stimulatory Factor 2, BSF-2, CTL Differentiation Factor, CDF, Interferon beta2, IFN-beta2

• Species:

  Human

• Protein ID:

  10834984

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3