IL-2 Recombinant Protein

• Background:

  Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL­2 shares 56% and 73% aa sequence identity with human and rat IL­2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma delta T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL­2 may be a key cytokine in the natural suppression of autoimmunity.

• NCBI Gene ID:

  16183

• Swiss Prot:

  P04351

• Accession Number:

  P04351

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Chemokines & Cytokines, Immunology

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM Sodium Citrate, 5% Trehalose, pH4.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  17.4 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Interleukin 2

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Aldesleukin, interleukin 2, interleukin-2, IL-2, IL2, T-cell growth facter, T cell growth factor, TCGF, REF: C1025

• Species:

  Mouse

• Protein ID:

  767957252

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3