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IL-16 Recombinant Protein

CAT: 0223-40-597Size: 0.01 mgDry Ice: NoHazardous: No
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CAT#:0223-40-597Size:0.01 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 12.4 kDa protein consisting of 121 amino acid residues. .
CAS Number
9000-83-3
NCBI Gene ID
3603
Swiss Prot
Q14005
Accession Number
NP_001165599.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Chemokines & Cytokines, Immunology
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized IL-16 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-16 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-16 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Interleukin 16
NCBI Organism
Homo sapiens
Other Product Names
LCF, NIL16, PRIL16, prIL-16, Pro-interleukin-16, Lymphocyte chemoattractant factor, IL-16
Species
Human
Protein ID
289063395
Physical Properties
Lyophilized

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