Histone Chaperone ASF1A Recombinant Protein

• Background:

  Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

• NCBI Gene ID:

  25842

• Swiss Prot:

  Q9Y294

• Accession Number:

  Q9Y294

• Tag:

  C-6 His, N-T7 tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 1mM DTT, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  25.4 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Anti-silencing function 1A histone chaperone

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Histone Chaperone ASF1A, Anti-Silencing Function Protein 1 Homolog A, hAsf1, hAsf1a, CCG1-Interacting Factor A, CIA, hCIA, ASF1A

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3