High Mobility Group Protein B1 Recombinant Protein

• Background:

  High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.

• NCBI Gene ID:

  3146

• Swiss Prot:

  P09429

• Accession Number:

  P09429

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Innate Immunity, Other

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, 1mM DTT, 10% Glycerol, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  25.93 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  High mobility group box 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  High Mobility Group Protein B1, High Mobility Group Protein 1, HMG-1, HMGB1, HMG1

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3