Hemoglobin alpha Recombinant Protein

• Background:

  Hemoglobin subunit alpha 1 (HBA1), also known as alpha2 beta 2, is a hetero-tetramer consisting of two alpha and two beta subunits held together by non-covalent interactions. Each subunit contains a heme group with an iron atom in the Fe2+ state. Cooperativity of Hemoglobin (Hb) in binding with O2 and allosteric regulatory binding properties with CO2, H+, Cl−, and 2,3-DPG (2,3-bisphosphoglycerate) are based on subunit interactions. HBA1 is the most common type of Hb in adult humans, which mediates the transport of oxygen and carbon dioxide in the blood. In recent years, Hb alpha and beta chains have been found co-expressed in alveolar cells, mesangial cells of the kidney, retinal ganglion cells, hepatocytes and neurons. Endothelial and peripheral catecholaminergic cells express exclusively the alpha chain, while macrophages present the beta chain only.

• NCBI Gene ID:

  3039

• Swiss Prot:

  P69905

• Accession Number:

  P69905

• Tag:

  N-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Other

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  16.7 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Hemoglobin subunit alpha 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1, HBH, HBA-T3

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3