GM-CSF Recombinant Protein

• Background:

  GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/macrophages, and eosinophils, GM-CSF has also been reported to have a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.

• NCBI Gene ID:

  1437

• Swiss Prot:

  P04141

• Accession Number:

  P04141

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  P. pastoris

• Field of Research:

  Growth Factors, Immunology, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 10mM TrisHCl, 4% Mannitol, 1% Sucrose, pH 8.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  14.4 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Colony stimulating factor 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Granulocyte-Macrophage Colony-Stimulating Factor, GM-CSF, Colony-Stimulating Factor, CSF, Molgramostin, Sargramostim, CSF2, GMCSF

• Species:

  Human

• Protein ID:

  767957252

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3