GM-CSF Recombinant Protein

• Background:

  GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.

• NCBI Gene ID:

  1437

• Swiss Prot:

  P04141

• Accession Number:

  NP_000749.2

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Growth Factors, Immunology, Signal Transduction

• Purity:

  Greater than 98% by SDS-PAGE gel and HPLC analyses.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized GM-CSF recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted GM-CSF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing GM-CSF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Colony stimulating factor 2 (granulocyte-macrophage)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GMCSF, GMCSF, Granulocyte-macrophage colony-stimulating factor, Colony-stimulating factor, GM-CSF

• Species:

  Human

• Protein ID:

  27437030

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3