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FGF-1 Recombinant Protein

CAT: 0223-90-317Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0223-90-317Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Fibroblast growth factors (FGFs) constitute a family of heparin-binding polypeptides involved in the regulation of biological responses such as growth, differentiation and angiogenesis. The biological effects of FGFs are mediated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3 and FGFR4. FGF-1 [FGF-acidic; ECGF; HBGF-1] is a powerful mitogen of cells of mesodermal, ectodermal and endodermal origin. FGF-1 association with heparan sulfate is a prerequisite for activation of FGF receptors. FGF-1 plays a role in various stages of development and morphogenesis as well as in angiogenesis and wound healing processes. Recent data indicate a role of FGF-1 in inflammation and obesity. FGF-1 is selectively induced in fat cells by high-fat diet feeding and established the PPARgamma-FGF-1 axis as a critical pathway that regulates adipose tissue remodeling.
CAS Number
9000-83-3
NCBI Gene ID
2246
Swiss Prot
Q04206
Accession Number
P05230
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Growth Factors
Concentration
0.1mg/ml after reconstitution.
Buffer
In PBS containing 0.2 mM DTT. Reconstitute with 100 μ l sterile water.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Fibroblast growth factor 1 (acidic)
NCBI Organism
Homo sapiens
Other Product Names
Fibroblast Growth Factor 1, Acidic Fibroblast Growth Factor, Endothelial Cell Growth Factor, ECGF, Heparin-binding Growth Factor 1, HBGF-1
Species
Human
Protein ID
122737
Physical Properties
Lyophilized

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