Ephrin B1 Recombinant Protein

• Background:

  Ephrin-B1 (EFNB1) is also known as EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2 (LERK-2), which belongs to the ephrin family. EFNB1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNB1 binds to the receptor tyrosine kinases EPHB1 and EPHA1. EFNB1 binds to, and induce the collapse of, commissural axons/growth cones in vitro. EFNB1 may play a role in constraining the orientation of longitudinally projecting axons. EFNB1 interacts with GRIP1 and GRIP2.

• NCBI Gene ID:

  1947

• Swiss Prot:

  P98172

• Accession Number:

  NP_004420

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  23.2 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Ephrin-B1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.

• Background Reference 02:

  Brueckner K., et al., 1999, Neuron 22:511-524.

• Other Product Names:

  EFNB1, EFL-3, ELK ligand, ELK-L, EPLG2, LERK2, CFND, CFNS

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3