Ephrin Type-B Receptor 1 Recombinant Protein

• Background:

  Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile alpha motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

• NCBI Gene ID:

  2047

• Swiss Prot:

  P54762

• Accession Number:

  P54762

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NaCl, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  48.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  EPH receptor B1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Ephrin Type-B Receptor 1, ELK, EPH Tyrosine Kinase 2, EPH-Like Kinase 6, EK6, hEK6, Neuronally-Expressed EPH, Related Tyrosine Kinase, NET, Tyrosine-Protein Kinase Receptor EPH-2, EPHB1, EPHT2

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3