Dentin matrix protein 1 Recombinant Protein

• Background:

  Dentin Matrix Acidic Phosphoprotein 1 (DMP-1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. DMP-1 is expressed in teeth particularly in odontoblast, ameloblast, and cementoblast. DMP-1 is critical for proper mineralization of bone and dentin. DMP-1 may have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, the unphosphorylated form of DMP-1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase, DMP-1 is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP-1 mutations have also been shown to cause rickets hypophosphatemic autosomal recessive type 1 (ARHR1) .

• NCBI Gene ID:

  1758

• Swiss Prot:

  Q13316

• Accession Number:

  Q13316

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cell Cycle, Signal Transduction, Stem Cell

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  55 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Dentin matrix acidic phosphoprotein 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Dentin Matrix Acidic Phosphoprotein 1, DMP-1, Dentin Matrix Protein 1, DMP1

• Species:

  Human

• Protein ID:

  767904139

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3