Cytochrome C Recombinant Protein

• Background:

  Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as a central component of the electron transport chain in mitochondria. CYCS transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase) . CYCS plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of Cytochrome C to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

• NCBI Gene ID:

  54205

• Swiss Prot:

  P99999

• Accession Number:

  P99999

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Apoptosis, Cancer, Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM Tris, 0.15M NaCl, 20% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  12.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Cytochrome c, somatic

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Cytochrome C, CYCS, CYC

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3