SARS-CoV-2 (COVID-19) Nucleocapsid Recombinant Protein

• Background:

  Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

• NCBI Gene ID:

  43740575

• Swiss Prot:

  QHD43423.2

• Accession Number:

  QHD43423.2

• Tag:

  N-6His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Infectious Disease, COVID-19

• Purity:

  Greater than 95% as determined by reducing SDS-PAGE.

• Buffer:

  Supplied as a 0.2 uM filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 1mM EDTA, pH 8.0.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Reconstituted protein solution should be store below -20˚ C.

• Calculated Molecular Weight:

  49.4kDa, 50-60kDa

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Nucleocapsid phosphoprotein

• NCBI Organism:

  Severe acute respiratory syndrome coronavirus 2

• Other Product Names:

  2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein

• Species:

  SARS-CoV-2 (COVID-19, 2019-nCoV) Nucleocapsid protein

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3