CD48 / SLAMF2 Recombinant Protein

• Background:

  CD48 antigen is also known as Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), Leukocyte antigen MEM-102, BCM1 surface antigen, B-lymphocyte activation marker BLAST-1. CD48 is a 65 kDa GPI-linked protein which belongs to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 antigen contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domain. CD48 interacts with CD244 in an heterophilic manner. CD48 is ligand for CD2. CD48 might facilitate interaction between activated lymphocytes. CD48 is probably involved in regulating T-cell activation.

• NCBI Gene ID:

  962

• Swiss Prot:

  P09326

• Accession Number:

  NP_001769.2

• Tag:

  Mouse IgG Fc Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Apoptosis, Cancer

• Purity:

  >95% as determined by SDS-PAGE.

• Buffer:

  50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  49.2 kDa

• Applications Notes:

  This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 49.2 kDa. The protein migrates as 64-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

• NCBI Official Name:

  CD48 molecule

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Korinek V., et al., 1991, Immunogenetics 33:108-112.

• Background Reference 02:

  Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.

• Other Product Names:

  CD48, BCM1, SLAMF2, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1

• Tested Applications:

  ELISA, WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3