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CEACAM5 Recombinant Protein

CAT: 0223-92-705Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-705Size:0.05 mg
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Background
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.
CAS Number
9000-83-3
NCBI Gene ID
1048
Swiss Prot
P06731
Accession Number
P06731
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Cell Cycle
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
98.9 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Carcinoembryonic antigen related cell adhesion molecule 5
NCBI Organism
Homo sapiens
Other Product Names
Carcinoembryonic antigen-related cell adhesion molecule 5, CEACAM5, Carcinoembryonic antigen, CEA, Meconium antigen 100, CD66e
Species
Human
Physical Properties
Lyophilized

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