Carboxypeptidase A1 Recombinant Protein

• Background:

  Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. It has a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 cleaves the C-terminal amide or ester bond of peptides and involves in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E.

• NCBI Gene ID:

  1357

• Swiss Prot:

  P15085

• Accession Number:

  P15085

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Other

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mm NaCl, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  46.57 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Carboxypeptidase A1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Carboxypeptidase A1, CPA1, CPA

• Species:

  Human

• Protein ID:

  20149322

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3