Anthrax Toxin Receptor 1 Recombinant Protein

• Background:

  Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI) .

• NCBI Gene ID:

  84168

• Swiss Prot:

  Q9H6X2

• Accession Number:

  Q9H6X2

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  Human Cells

• Field of Research:

  Cancer, Infectious Disease, Neuroscience

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  33.56 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Anthrax toxin receptor 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Anthrax Toxin Receptor 1, Tumor Endothelial Marker 8, ANTXR1, ATR, TEM8

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3