7-Deaza-2′-deoxyguanosine 5′-triphosphate

7-Deaza-2′-deoxyguanosine 5′-triphosphate

• CAS Number: 101515-08-6
• UNSPSC Description: 7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM)[1].
• Target Antigen: Telomerase
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/7-deaza-2-deoxyguanosine-5-triphosphate.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1C[C@H](N2C(N=C(N)NC3=O)=C3C=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O
• Molecular Weight: 506.19
• References & Citations: [1]Fletcher TM, et al. Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates. Biochemistry. 1996 Dec 10;35(49):15611-7.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported