Defensin HNP 4

Defensin HNP 4

• UNSPSC Description: Defensin HNP 4 (HNP 4) is a single 11 amino acid long fragment of HNP-41-11. Defensin HNP 4 has inhibitory effect against multidrug-resistant and non-resistant strains[1].
• Target Antigen: Bacterial
• Type: Peptides
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/defensin-hnp-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H](CSSC[C@@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)NC1=O)C(N[C@@H](CO)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(NCC(NCC(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H]([C@H](O)C)C(N[C@H]3CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC5=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CSSC[C@@H]1NC3=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(NCC(N[C@H]5CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
• Molecular Weight: 3709.40
• References & Citations: [1]Ehmann D, et al. Fragmentation of Human Neutrophil α-Defensin 4 to Combat Multidrug Resistant Bacteria. Front Microbiol. 2020 Jun 3;11:1147.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported