H-D-Phe-Pip-Arg-pNA (hydrochloride)

H-D-Phe-Pip-Arg-pNA (hydrochloride)

• Product Name Alternative: S-2238 (hydrochloride)
• CAS Number: 160192-34-7
• UNSPSC Description: H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform[1][2].
• Target Antigen: Fluorescent Dye
• Type: Peptides
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/h-d-phe-pip-arg-pna-hydrochloride.html
• Purity: 99.35
• Solubility: H2O : 250 mg/mL (ultrasonic)
• Smiles: O=C([C@H](N)CC1=CC=CC=C1)N2[C@H](C(N[C@@H](CCCNC(N)=N)C(NC3=CC=C([N+]([O-])=O)C=C3)=O)=O)CCCC2.Cl
• Molecular Weight: 589.09
• References & Citations: [1]Goodnight SH Jr, et al. Measurement of antithrombin III in normal and pathologic states using chromogenic substrate S-2238. Comparison with immunoelectrophoretic and factor Xa inhibition assays. Am J Clin Pathol. 1980;73(5):639-647.|[2]van Voorthuizen H, Kluft C. Improved assay conditions for automated antithrombin III determinations with the chromogenic substrate S-2238. Thromb Haemost. 1984;52(3):350-353.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported