Guanylyl imidodiphosphate (lithium)

• UNSPSC Description:

  Guanylyl imidodiphosphate (Gpp(NH)p) lithium, a non-hydrolyzable GTP analogue, increases adenylate cyclase activity[1][2].

• Target Antigen:

  Adenylate Cyclase

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/guanylyl-imidodiphosphate-lithium.html

• Smiles:

  O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](N[P](O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O)([H])N2C(NC(N)=NC3=O)=C3N=C2

• Molecular Weight:

  545.93

• References & Citations:

  [1]B J Terry, et al. Assembly and disassembly properties of microtubules formed in the presence of GTP, 5'-guanylyl imidodiphosphate, and 5'-guanylyl methylenediphosphate. J Biol Chem. 1980 Nov 10;255(21):10532-6.|[2]H Abou-Issa, et al. Modulation of follicle-stimulating hormone-sensitive rat testicular adenylate cyclase activity by guanyl nucleotides. Endocrinology. 1979 Jan;104(1):189-93.

• Shipping Conditions:

  Blue Ice

• CAS Number:

  64564-03-0