Guanylyl imidodiphosphate (lithium)

Guanylyl imidodiphosphate (lithium)

• CAS Number: 64564-03-0
• UNSPSC Description: Guanylyl imidodiphosphate (Gpp(NH)p) lithium, a non-hydrolyzable GTP analogue, increases adenylate cyclase activity[1][2].
• Target Antigen: Adenylate Cyclase
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Field of Research: Endocrinology
• Assay Protocol: https://www.medchemexpress.com/guanylyl-imidodiphosphate-lithium.html
• Smiles: O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](N[P](O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O)([H])N2C(NC(N)=NC3=O)=C3N=C2
• Molecular Weight: 545.93
• References & Citations: [1]B J Terry, et al. Assembly and disassembly properties of microtubules formed in the presence of GTP, 5'-guanylyl imidodiphosphate, and 5'-guanylyl methylenediphosphate. J Biol Chem. 1980 Nov 10;255(21):10532-6.|[2]H Abou-Issa, et al. Modulation of follicle-stimulating hormone-sensitive rat testicular adenylate cyclase activity by guanyl nucleotides. Endocrinology. 1979 Jan;104(1):189-93.
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