Terbinafine

CAT: 0804-HY-17395A-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-17395A-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria[1][2][3]. Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[91161-71-6]
Product Name Alternative
TDT 067
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Terbinafine.html
Purity
99.96
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CN(C/C=C/C#CC(C)(C)C)CC1=C2C=CC=CC2=CC=C1
Molecular Formula
C21H25N
Molecular Weight
291.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Ryder NS, et al. Terbinafine: mode of action and properties of the squalene epoxidase inhibition. Br J Dermatol. 1992 Feb;126 Suppl 39:2-7.|[2]Mieth H, et al. Preclinical evaluation of terbinafine in vivo. Clin Exp Dermatol. 1989 Mar;14 (2) :104-7.|[3]Ciftci E, et al. Mupirocin vs terbinafine in impetigo.Indian J Pediatr. 2002 Aug;69 (8) :679-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Adv Healthc Mater. 2023 Sep;12 (22) :e2300018.|Adv Sci (Weinh) . 2023 Sep;10 (27) :e2206878.|Autophagy. 2025 May 9:1-18.|bioRxiv. 2024 May 14.|Cancer Commun (Lond) . 2021 Aug;41 (8) :726-746.|Cancer Lett. 2025 Oct 10:630:217901.|Clin Transl Med. 2024 Feb;14 (2) :e1586.|Infect Drug Resist. 2022 Dec 15:15:7459-7473.|J Orthop Surg Res. 2025 Oct 17;20 (1) :894.|Nat Microbiol. 2024 Feb;9 (2) :346-358.|Research Square Preprint. 2023 Sep 26.|Cancer Res. 2022 Sep 2;82 (17) :3032-3044.|Cell Death Dis. 2021 May 13;12 (5) :482.

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