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N-Desmethylolanzapine

CAT: 0804-HY-W009247-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W009247-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-Desmethylolanzapine is an antipsychotic drug. The formation of N-Desmethylolanzapine correlates with the level and activity of human liver flavin-containing monooxygenase (FMO3) . N-Desmethylolanzapine can be used in the study of antipsychotic drugs [1].
CAS Number
161696-76-0
Product Name Alternative
N-Demethylolanzapine; LY170055
UNSPSC
12352005
Hazard Statement
H225, H302, H319
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/n-desmethylolanzapine.html
Purity
98.0
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
CC(S1)=CC2=C1NC3=CC=CC=C3N=C2N4CCNCC4
Molecular Formula
C16H18N4S
Molecular Weight
298.42
Precautions
H225, H302, H319
References & Citations
[1]Ring BJ, et al. Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine. J Pharmacol Exp Ther. 1996 Feb;276 (2) :658-66.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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