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POMC Antibody

CAT: 0013-GTR18193166-02Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18193166-02Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal antibody to MSH Alpha
Product Name Alternative
Anti MSH Alpha antibody, anti alpha melanocyte stimulating hormone antibody, anti Alpha MSH antibody, anti Melanotropin alpha antibody, anti POMC antibody, anti proopiomelanocortin antibody, anti Alpha-MSH antibody
UniProt
P01189
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide corresponding to aa1-24 of human ACTH
Target
POMC
Clonality
Monoclonal
Clone
AH26
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Neuroscience, Signal Transduction
Dilution
FACS: 0.5-1 μg/million cells, IF/ICC: 1-2 μg/ml, IHC-P: 0.5-1 μg/ml
Form
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
Molecular Weight
ACTH is ~5kDa|and the POMC precursor is ~30kDa. The molecular weight of POMC depends upon isoform variation and post-translational modifications.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker)
Tested Applications
FC, IF, IHC
Host or Source
Mouse
Isotype
IgG1

UniProtKB · P01189

Pro-opiomelanocortin

COLI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01189
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POMC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
POMC
EC number
—
Processing
Precursor
Secondary accessions
P78442, Q53T23, Q9UD39, Q9UD40
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationAmidationCleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoprotein

Molecular function

EndorphinHormone

Disease

Obesity

Cellular component

Secreted

Domain

Signal

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