KIT Antibody

CAT: 0013-GTR18193109-02Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0013-GTR18193109-02Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Mouse monoclonal antibody to c-Kit

Product Name Alternative

Anti-C Kit antibody, anti-c-kit antibody, anti-CD 117 antibody, anti-CD117 antibody, anti-CD117 antigen antibody, anti-KIT antibody, anti-KIT oncogene antibody, anti-Mast cell growth factor receptor antibody, anti-Mast/stem cell growth factor receptor antibody, anti-Mast/stem cell growth factor receptor Kit antibody, anti-p145 c-kit antibody, anti-PBT antibody, anti-Piebald trait protein antibody, anti-Proto oncogene c Kit antibody, anti-Proto oncogene tyrosine protein kinase Kit antibody, anti-Proto-oncogene c-Kit antibody, anti-SCF Receptor antibody, anti-SCFR antibody, anti-soluble KIT variant 1 antibody, anti-Steel Factor Receptor antibody, anti-Stem cell factor receptor antibody, anti-tyrosine protein kinase Kit antibody, anti-Tyrosine-protein kinase Kit antibody

UniProt

P10721

Reactivity

Human

Immunogen

Recombinant human CD117 protein

Target

KIT

Clonality

Monoclonal

Clone

C117/370

Conjugation

Unconjugated

Field of Research

Cancer Biology, Cardiovascular Research, Epigenetics & Chromatin, Hematology, Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Dilution

FACS: 0.5-1 μg/million cells, IF/ICC: 0.5-1 μg/ml, IHC-P: 0.5-1 μg/ml

Form

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.

Molecular Weight

145kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors)

Tested Applications

IHC

Host or Source

Mouse

Isotype

IgG2b

UniProtKB · P10721

Mast/stem cell growth factor receptor Kit

KIT_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P10721
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: KIT
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: SCFR
EC number: 2.7.10.1
Processing: Precursor
Secondary accessions: B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmMembrane

Disease

Disease variantProto-oncogene

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

KinaseReceptorTransferaseTyrosine-protein kinase

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