(-)-Blebbistatin

• UNSPSC Description:

  (-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II[1][2].

• Target Antigen:

  Myosin

• Type:

  Reference compound

• Related Pathways:

  Cytoskeleton

• Field of Research:

  Cardiovascular Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/_-_-Blebbistatin.html

• Smiles:

  CC1=CC=C(N=C(N(C2=CC=CC=C2)CC3)[C@]3(O)C4=O)C4=C1

• Molecular Weight:

  292.338

• References & Citations:

  [1]Cristina Lucas‐Lopez, et al. Absolute Stereochemical Assignment and Fluorescence Tuning of the Small Molecule Tool, (–)‐Blebbistatin.|[2]Ponsaerts R, et al. The myosin II ATPase inhibitor blebbistatin prevents thrombin-induced inhibition of intercellularcalcium wave propagation in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2008 Nov;49(11):4816-27.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  856925-71-8