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Oxazosulfyl

CAT: 0804-HY-136330-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136330-01Size:5 mg
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Description
Oxazosulfyl is a sulfyl insecticide with potent and cross-spectrum insecticidal activity. Oxazosulfyl inhibits sodium currents by binding to and stabilizing the slow-inactivated state of voltage-gated sodium channels, leading to insect paralysis. Oxazosulfyl's ability to block sodium channels is correlated with its insecticidal activity[1][2].
CAS Number
1616678-32-0
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
Insecticide; Parasite; Sodium Channel
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/oxazosulfyl.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(OC(C2=NC=CC=C2S(=O)(CC)=O)=N3)C3=C1)(C(F)(F)F)=O
Molecular Formula
C15H11F3N2O5S2
Molecular Weight
420.38
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
[1]Rosemary Lees, et al. A Testing Cascade to Identify Repurposed Insecticides for Next-Generation Vector Control Tools: Screening a Panel of Chemistries With Novel Modes of Action Against a Malaria Vector. Gates Open Res. 2019 Jul 10;3:1464.|[2]Suzuki T, et al. Oxazosulfyl, a Novel Sulfyl Insecticide, Binds to and Stabilizes the Voltage-Gated Sodium Channels in the Slow-Inactivated State. J Agric Food Chem. 2021 Apr 14;69 (14) :4048-4055.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
TRC-O977660-100MGOxazosulfyl

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