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Vibozilimod

CAT: 0804-HY-132847-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132847-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vibozilimod (SCD-044, Example 33) is an orally active and selective S1PR1/EDG1 agonist with an EC50 of less than 1 nM. Vibozilimod has immunomodulatory activity and can reduce the number of lymphocytes. Vibozilimod can be used in the research of inflammatory diseases such as psoriasis and atopic dermatitis[1][2].
CAS Number
1403232-33-6
Product Name Alternative
SCD-044
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vibozilimod.html
Purity
99.52
Solubility
Ethanol : 1.92 mg/mL (ultrasonic; warming; adjust pH to 5 with HCl; heat to 60°C)
Smiles
O=C(C1(COCCOC)CCN(CC2=CC=C(C3=NOC(C4=CC=C(CC(C)C)C(Cl)=C4)=N3)C=C2)CC1)O
Molecular Formula
C29H36ClN3O5
Molecular Weight
542.07
References & Citations
[1]Marc Capet, et al. Novel piperidinyl monocarboxylic acids as s1p1 receptor agonists. Patent. WO2012140020A1. 2012-10-18.|[2]Drakos A, et al. A Review of the Clinical Trial Landscape in Psoriasis: An Update for Clinicians. Dermatol Ther (Heidelb) . 2022 Dec;12 (12) :2715-2730.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
S1PR1

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