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CK19 Polyclonal Antibody

CAT: 0763-D-AB-10360L-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-D-AB-10360L-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
Abbreviation
CK19
UniProt
Q63279
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Rat Krt19 protein expressed by E.coli
Target
40 kDa keratin intermediate filament; CK 19; CK-19; CK19; Cytokeratin 19; Cytokeratin-19; K19; K1C19; K1CS; Keratin 19; Keratin type I 40 kD; Keratin type I 40kD; Keratin type I cytoskeletal 19; Keratin; type I cytoskeletal 19; Keratin; type I; 40 kd; Keratin-19; KRT19
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Signal Transduction
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q63279

Keratin, type I cytoskeletal 19

K1C19_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
Q63279
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Krt19
Protein existence
1: Evidence at protein level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0JN08, Q5M7V2, Q6S6J4, Q9Z253
Protein keywords

Domain

Coiled coil

Technical term

Direct protein sequencingReference proteome

Cellular component

Intermediate filamentKeratin

PTM

MethylationPhosphoprotein

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