Recombinant AURKB Protein

• Description:

  Recombinant AURKB Protein_x000D_ Catalog number: B2017474_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 20 µg_x000D_ Molecular Weight or Concentration: 40.5 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Aurora kinase B_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: López-Carrasco A, Oltra S, Monfort S, Mayo S, Roselló M, Martínez F, Orellana C. Mutation screening of AURKB and SYCP3 in patients with reproductive problems Mol Hum Reprod. 2013 Feb;19(2):102-8._x000D_ 2: Lee KB, Jin H, Ye S, Park BH, Kim SM. Recombinant human bone morphogenetic protein-2 inhibits gastric cancer cell proliferation by inactivating Wnt signaling pathway via c-Myc with aurora kinases Oncotarget. 2016 Nov 8;7(45):73473-73485._x000D_ 3: Carmena M, Ruchaud S, Earnshaw WC. Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins Curr Opin Cell Biol. 2009 Dec;21(6):796-805._x000D_ 4: den Hollander J, Rimpi S, Doherty JR, Rudelius M, Buck A, Hoellein A, Kremer M, Graf N, Scheerer M, Hall MA, Goga A, von Bubnoff N, Duyster J, Peschel C, Cleveland JL, Nilsson JA, Keller U. Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state Blood. 2010 Sep 2;116(9):1498-505._x000D_ 5: He SJ, Shu LP, Zhou ZW, Yang T, Duan W, Zhang X, He ZX, Zhou SF. Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells Cancer Lett. 2016 Nov 28;382(2):215-230._x000D_ 6: Noor S, Choudhury A, Raza A, Ashraf A, Islam KU, Hussain A, Imtiyaz K, Islam A, Hassan MI. Probing Baicalin as potential inhibitor of Aurora kinase B: A step towards lung cancer therapy Int J Biol Macromol. 2024 Feb;258(Pt 1):128813._x000D_ 7: Wellard SR, Schindler K, Jordan PW. Aurora B and C kinases regulate chromosome desynapsis and segregation during mouse and human spermatogenesis J Cell Sci. 2020 Dec 4;133(23):jcs248831._x000D_ 8: Park H, Kim H, Hassebroek V, Azuma Y, Slawson C, Azuma M. Chromosomal localization of Ewing sarcoma EWSR1/FLI1 protein promotes the induction of aneuploidy J Biol Chem. 2021 Jan-Jun;296:100164._x000D_ 9: Han X, Zhang JJ, Han ZQ, Zhang HB, Wang ZA. Let-7b attenuates cisplatin resistance and tumor growth in gastric cancer by targeting AURKB Cancer Gene Ther. 2018 Dec;25(11-12):300-308._x000D_ 10: Zhu L, Wang Z, Wang W, Wang C, Hua S, Su Z, Brako L, Garcia-Barrio M, Ye M, Wei X, Zou H, Ding X, Liu L, Liu X, Yao X. Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis J Biol Chem. 2015 Nov 6;290(45):27053-27066. _x000D_ _x000D_ Products Related to Recombinant AURKB Protein can be found at Proteins

• Short Description:

  Catalog Number: B2017474 (20 µg)_x000D_ Recombinant AURKB protein is produced using recombinant DNA technology. AURKB, or Aurora kinase B, is vital in cell division and chromosome segregation during mitosis. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3