Hexapeptide-11

• UNSPSC Description:

  Hexapeptide-11 is a bioactive peptide with anti-aging effect. Hexapeptide-11 protects fibroblasts against oxidative stress-mediated premature cellular senescence by mediating a downregulation of cellular proteins, such as ataxia telangiectasia mutated (ATM) and p53 [1].

• Target Antigen:

  ATM/ATR; MDM-2/p53; Reactive Oxygen Species

• Type:

  Peptides

• Related Pathways:

  Apoptosis;Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;PI3K/Akt/mTOR

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/hexapeptide-11.html

• Purity:

  99.52

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(O)[C@H]1N(C([C@H](CC2=CC=CC=C2)NC([C@H]3N(C([C@H](C)NC([C@H](C(C)C)NC([C@H](CC4=CC=CC=C4)N)=O)=O)=O)CCC3)=O)=O)CCC1

• Molecular Weight:

  676.80

• References & Citations:

  [1]Errante F, et al. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy. Front Chem. 2020;8:572923.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  161258-30-6