SB03178

CAT: 0804-HY-161262Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-161262Size:1 Each

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Description

SB03178 is a fibroblast activation protein-alpha (FAP) inhibitor. SB03178 can be conjugated with DOTA and can be used for cancer research[1].

CAS Number

2952588-12-2

UNSPSC

12352005

Target

FAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sb03178.html

Solubility

10 mM in DMSO

Smiles

OC(CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(N2CCN(CCCOC3=CC4=C(C(NCC(N5[C@H](C#N)CC(F)(F)C5)=O)=O)C=CN=C4C6=C3C=CC=C6)CC2)=O)CC1)=O

Molecular Formula

C44H56F2N10O10

Molecular Weight

922.97

References & Citations

[1]Bendre S, et al. Development, preclinical evaluation and preliminary dosimetry profiling of SB03178, a first-of-its-kind benzo[h]quinoline-based fibroblast activation protein-α-targeted radiotheranostic for cancer imaging and therapy. Eur J Med Chem. 2024 Feb 13;268:116238.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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GTR19234664-01	SB03178

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