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IM156

CAT: 0026-B3126-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B3126-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IM156 is a bioenergetic biguanide derivative which blocks mitochondrial complex I and an activator of AMP-activated protein kinase (AMPK). It is a derivative of metformin. IM156 causes energy depletion in tumor cells by inhibiting oxidative phosphorylation. IM156 at a concentration of 15 μM in combination with temozolomide decreases the stemness and invasive properties of glioblastoma tumorspheres. IM156 is in phase I clinical trials for advanced solid tumors and lymphoma.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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