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Ibalizumab

CAT: 0804-HY-P99028-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99028-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ibalizumab (TMB-355) is a humanized anti-CD4 IgG4 monoclonal antibody. Ibalizumab prevents HIV cell entry by binding to CD4 receptor. Ibalizumab can be used for the research of infection, such as HIV-1 infection[1][2].
CAS Number
680188-33-4
Product Name Alternative
TMB-355; TNX-355
UNSPSC
12352203
Target
HIV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ibalizumab.html
Purity
99.91
Solubility
H2O
Smiles
[Ibalizumab]
Molecular Weight
(147.36 kDa)
References & Citations
[1]Zhu L, et al. Highly potent and broadly neutralizing anti-CD4 trimeric nanobodies inhibit HIV-1 infection by inducing CD4 conformational alteration. Nat Commun. 2024 Aug 13;15 (1) :6961.|[2]Beccari MV, et al. Ibalizumab, a Novel Monoclonal Antibody for the Management of Multidrug-Resistant HIV-1 Infection. Antimicrob Agents Chemother. 2019 May 24;63 (6) :e00110-19.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched
Isoform
HIV-1

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