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Human CellExp™ PON1, Human Recombinant

CAT: 0026-P1556-10Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0026-P1556-10Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PON1, also known as A esterase1, is a member of the paraoxonase family. It is an enzyme that hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). This protein is activated by PPAR-gamma, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis. PON1 shows a variety of atheroprotective properties by metabolizing inflammatory lipid peroxides. It has evolved to be a highly promiscuous enzyme capable of hydrolysing a wide variety of substrates such as lactones, cyclic carbonates, organophosphorus pesticides and nerve gases. Recombinant human PON1, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
12 months

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