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ACK1, Human Recombinant

CAT: 0026-P1499-50Size: 50 µgDry Ice: YesHazardous: No
CAT#:0026-P1499-50Size:50 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Activated CDC42 kinase 1, also known as ACK1, is an enzyme that is encoded by the TNK2 gene in humans. TNK2 gene encodes a non-receptor tyrosine kinase, ACK1, that binds to multiple receptor tyrosine kinases e.g. EGFR, MERTK, AXL, HER2 and insulin receptor (IR). ACK1 also interacts with Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain.
CAS Number
9000-83-3
Shipping Conditions
Dry Ice
Storage Conditions
-70°C
Shelf Life
12 months

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