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JTE-607

CAT: 0026-B3064-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B3064-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JTE-607 is a multiple cytokine inhibitor. It inhibits cytokine production specifically in human peripheral blood mononuclear cells without causing immunosuppression. It inhibits tumor necrosis factor-α (TNF-α), interleukins IL-1β, IL-6, IL-8 and IL-10 from LPS-stimulated human PBMCs with IC₅₀ values of 11 nM, 5.9 nM, 8.8 nM, 7.3 nM and 9.1 nM, respectively. It (0.4-0.8 μM) also inhibits the growth of acute myelogenous leukemia cell lines by inducing apoptosis and cell-cycle arrest.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36months

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