BAY-1816032

• Description:

  BAY-1816032 is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7 nM. Displays excellent selectivity over a panel of 395 kinases. BAY 1816032 abrogates nocodazole-induced Thr-120 phosphorylation of the major BUB1 target protein histone H2A in HeLa cells with an IC50 of 29 nanomol/L, induces lagging chromosomes and mitotic delay.

• Shipping Conditions:

  Gel Pack

• Storage Conditions:

  -20ºC

• Shelf Life:

  36 months