Astemizole

CAT: 0026-B3050-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B3050-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Astemizole is a histamine H1-receptor antagonist, with an IC₅₀ of 4 nM. Astemizole also shows potent hERG potassium channel blocking activity with an IC₅₀ of 0.9 nM. Astemizole shows synergistic antiproliferative effects with calcitriol in breast cancer cells and in vivo preclinical models by blocking the EAG1 potassium channel. High throughput screens have shown that astemizole is a promising candidate for stopping replication of SARS-CoV-2 virus.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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