N4-Hydroxycytidine
CAT:
26-B3039-5
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
N4-Hydroxycytidine
- Description: N4-Hydroxycytidine is a ribonucleoside analog with broad-spectrum antiviral activity. The prodrug of N4-hydroxycytidine is EIDD-2801. N4-Hydroxycytidine is active against influenza, Ebola, Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)and Venezuelan equine encephalitis virus (VEEV). It inhibits replication of SARS-CoV-2 and Middle East respiratory syndrome coronavirus (MERS-CoV) in Calu-3 2B4 cells with IC₅₀ values of 0.08 μM and 0.15 μM respectively. N4-Hydroxycytidine (100 and 400 mg/kg twice per day) reduces lung viral titers in a mouse model of Respiratory Syncytial Virus (RSV) infection.
- Shipping Conditions: Gel Pack
- Storage Conditions: -20ºC
- Shelf Life: 36 months