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Adapalene

CAT: 0026-B2733-10Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0026-B2733-10Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Adapalene is a synthetic Retinoic acid analog that acts as a RARβ and RARγ agonist (AC₅₀ values are 2.2, 9.3, 22 and > 1000 nM for RARβ, RAR��, RARα and RXRα receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cells in vitro. Adapalene (10 μM) completely inhibits the activity of soybean 15-lipoxygenase (15-LOX) in an enzyme assay and inhibits the 5- and 15-LOX pathways in human blood polymorphonuclear leukocytes (PMNs).
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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