AMG-517
CAT:
26-B3019-5
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AMG-517
- Description: AMG-517 is an antagonist of transient receptor potential vanilloid 1 (TRPV1) with an IC₅₀ of 0.9 nM. It inhibits post-burn mechanical and thermal allodynia in a rat model of burn injury when administered intrathecally at a dose of 165 µg. It (150 and 300 µg/kg) decreases calcitonin gene-related peptide (CGRP) release from spinal dorsal horn and promotes peripheral nerve regeneration in a rat model of sciatic nerve transection injury.
- Shipping Conditions: RT
- Storage Conditions: -20ºC
- Shelf Life: 36 months