AMG-517

CAT: 0026-B3019-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B3019-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMG-517 is an antagonist of transient receptor potential vanilloid 1 (TRPV1) with an IC₅₀ of 0.9 nM. It inhibits post-burn mechanical and thermal allodynia in a rat model of burn injury when administered intrathecally at a dose of 165 µg. It (150 and 300 µg/kg) decreases calcitonin gene-related peptide (CGRP) release from spinal dorsal horn and promotes peripheral nerve regeneration in a rat model of sciatic nerve transection injury.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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