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WIN 55,212-2 Mesylate

CAT: 0026-B3012-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B3012-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(+)-WIN 55,212-2 (mesylate) is a potent aminoalkyl indole cannabinoid (CB) receptor agonist with Ki values of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. It shows antihyperalgesic and anti-inflammatory properties. It (0.01-100 nM) increases extracellular glutamate levels, displaying a bell-shaped concentration-response curve in primary cultures of rat cerebral cortex neurons. It also evokes CGRP release from trigeminal ganglion neurons in vitro (EC₅₀=26 μM) in a concentration- and calcium-dependent manner.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months