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CA-074

CAT: 0026-B2971-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2971-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CA-074 is an epoxysuccinyl peptide inhibitor of cathepsin B. It selectively inhibits cathepsin B with an IC₅₀ of 2.24 nM over other cysteine proteinases such as cathepsins L and H, and calpains. It inhibits cathepsins H, L and calpain with IC₅₀ values of 172 μM, 420 μM and 200 μM. Intraperitoneal administration (50 mg/kg) of CA-074 reduces metastasis in 4T1.2 mouse xenograft model. It reduces mercury induced expression of inflammatory cytokines in mice.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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