666-15

CAT: 0026-B2970-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2970-5Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
666-15 is a potent and selective inhibitor of cyclic adenosine monophosphate response element binding protein (CREB)-mediated gene transcription with an IC₅₀ of 81 nM. The IC₅₀ values for inhibiting the growth of A549, MCF-7, MDA-MB-231, MDA-MB-468 cell lines are 0.47 μM, 0.31 μM, 0.073 μM, 0.046 μM respectively. It is a weak inhibitor of CREB-CBP (CREB-binding protein) interaction with an IC₅₀ of 18.27 μM. Intraperitoneal injection of 666-15 at 10 mg/kg/day, 5 days per week for 5 weeks suppresses tumor growth in an in vivo MDA-MB-468 xenograft model.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36months

Related Products

CatalogName
B2147-5C K-666
B2147-25C K-666
5171-100IL-15 Antibody
9583-5P505-15 hydrochloride
9583-25P505-15 hydrochloride
5172-100IL-15 Antibody
4569-20GDF-15, human recombinant
4569-1000GDF-15, human recombinant
A2038-100Anti-GDF-15 Antibody
4171-10IL-15, murine recombinant

Alternative Products

CatalogName
5661/50666-15
A18344-50666-15 50mg
A18344-100666-15 100mg
A18344-1666-15 1mg
A18344-10666-15 10mg
HY-101120R666-15 (Standard)
A18344-25666-15 25mg
A18344-5666-15 5mg
C13715-01Compound 3i (666-15)
A18344-10mM-D666-15 10mM * 1mL in DMSO

Popular Products