P505-15 hydrochloride

CAT: 0026-9583-5Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0026-9583-5Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

P505-15 is a potent, cell-permeable, highly selective, small molecule SYK inhibitor (IC₅₀ = 1 nM) with anti-SYK activity that is at least 80-fold greater than its affinity for other kinases. P505-15 blocks B cell receptor-mediated cell signaling and activation in whole blood (IC₅₀s = 0.27 and 0.28 µM, respectively), as well as Fcɛ receptor 1-mediated basophil degranulation (IC₅₀ = 0.15 µM).

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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P505-15 hydrochloride

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